MLH1 甲基化單基因單區(qū)段標(biāo)準(zhǔn)品
CBPE0257-0263
詢 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| Introduction | ||||||
| Description | DNA methylation is an epigenetic modification, a form of chemical modification of DNA, which refers to the carbon 5 of cytosine in the genomic CpG dinucleotide under the action of DNA methyltransferase. covalently bonded to a methyl group. It can change genetic expression without changing the DNA sequence. MLH1, mutL homolog 1, is a tumor suppressor that dimerizes with Pms2 to form a component of the DNA mismatch repair (MMR) system, and is associated with microsatellite instability (MSI) and genomic stability. |
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| Technical Data | ||||||
| Classification | Cat No. | Name | Unit Size | Methylation level | ||
| Chr3:37034735-37034852(hg19) | ||||||
| 質(zhì)控品 | 陽性質(zhì)控品 | CBPE0257 | MLH1 Methylation Positive control | 1ug | 98.59% | |
| 陰性質(zhì)控品 | CBPE0258 | MLH1 Methylation Negative control (< Cut off) | 1ug | 0.00% | ||
| 參考品 | 強(qiáng)陽性參考品-1 | CBPE0259 | MLH1 Methylation Reference Standard with > 90% | 1ug | 98.59% | |
| 強(qiáng)陽性參考品-2 | CBPE0260 | MLH1 Methylation Reference Standard with 10% | 1ug | 10.10% | ||
| 弱陽性參考品 | CBPE0261 | MLH1 Methylation Reference Standard with 3% | 1ug | N/A | ||
| 檢測(cè)限參考品 | CBPE0262 | MLH1 Methylation Reference Standard with 1% | 1ug | 0.98% | ||
| 陰性參考品 | CBPE0263 | MLH1 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
| 精密度參考品 | CBPE0261 | MLH1 Methylation Reference Standard with 3% | 1ug | N/A | ||
| CBPE0263 | MLH1 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |||
| 特異性參考品 | 定制化 | |||||
| 備注 | 1. 質(zhì)控品也叫準(zhǔn)確度標(biāo)準(zhǔn)品，用于定性判斷； 2. 參考品用于定性和定量的判斷，其中強(qiáng)陽、弱陽、檢測(cè)限、精密度、特異性的判定需要視具體項(xiàng)目而定，本產(chǎn)品的判定僅為內(nèi)部標(biāo)準(zhǔn)； 3. 質(zhì)控品用于性能評(píng)價(jià)，出廠檢，試劑盒日常檢測(cè)判定，參考品用于性能評(píng)價(jià)，出廠檢； 4.上述產(chǎn)品只展示了部分結(jié)果，甲基化程度可以定制。 |
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| Product Information | ||||||
| Intended Use | Research Use Only | |||||
| Concentration | Download for COA | |||||
| Purity | Download for COA | |||||
| DNA electrophoresis | Download for COA | |||||
| Storage | 2-8°C | |||||
| Expiry | 36 months from the date of manufacture | |||||
| Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. | |||||
